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. 2016 Aug 9;111(3):601–608. doi: 10.1016/j.bpj.2016.06.023

Figure 4.

Figure 4

CHO cells confirm the role of GPIbα in force transmission. Representative images of CHOαβIX cells on microposts coated with (A) VWF, (B) recombinant A1 domain, or (C) CHOαΔ534βIX cell, or (D) CHOαFW-AAβIX cell on VWF-coated microposts (green: actin, red: post, blue: nucleus). (E) Spread area and (F) contractile forces for CHOαβIX and CHOβIX cells (N = 5 replicate experiments). (G) Spread area and (H) contractile forces of CHOαβIX cells treated with or without blebbistatin (N = 3 replicate experiments). (I) Spread area and (J) contractile forces for CHOαβIX, CHOαΔ534βIX, or CHOαFW-AAβIX cells (N = 4 replicate experiments). Scale bars represent 6 μm, force scale bars represent 30 nN, and the error bars represent the standard error of the mean. Asterisk denotes p-value <0.05. To see this figure in color, go online.