Figure 7.

Roles of Celsr1 in fold-pattern formation. Summary of the roles of Celsr1 in fold-pattern formation showing their relationships to cell-shape polarization, epithelial tension, and L-Epi/SM ratio. Cartoons of epithelial cell sheets are shown, with Celsr1 proteins (green) localized and epithelial tension indicated (blue and orange arrows), in wild-type (WT) and Celsr1^−/− situations. The L-Epi/SM ratio and the longitudinal epithelial tension are mutually dependent. Fold shapes are also illustrated. See the main text. To see this figure in color, go online.