Table 4.
Top 20 functional categories of predicted gene targets by uniquely expressed miRNAs in sera and exosomes
| Sera | Exosomes | ||
|---|---|---|---|
| Category | B-H p-value | Category | B-H p-value |
| Cellular Growth and Proliferation | 1.27E-28-1.11E-03 | Cellular Growth and Proliferation | 2.76E-12-6.05E-02 |
| Cancer | 4.54E-24-1.01E-03 | Cancer | 1.26E-08-6.05E-02 |
| Organismal Injury and Abnormalities | 4.54E-24-1.11E-03 | Organismal Injury and Abnormalities | 1.26E-08-6.05E-02 |
| Cell Death and Survival | 5.07E-24-1.01E-03 | Cell Morphology | 1.67E-08-6.05E-02 |
| Organismal Survival | 5.07E-24-2.65E-06 | Organismal Survival | 3.05E-08-2.39E-02 |
| Cellular Assembly and Organization | 7.61E-20-4.99E-04 | Cellular Assembly and Organization | 6.75E-07-6.05E-02 |
| Cellular Function and Maintenance | 7.61E-20-8.07E-04 | Cellular Function and Maintenance | 6.75E-07-6.05E-02 |
| Cell Morphology | 8.22E-19-7.27E-04 | Cellular Movement | 3.04E-06-6.03E-02 |
| Molecular Transport | 2.63E-16-9.67E-04 | Cell Death and Survival | 3.43E-06-6.03E-02 |
| Cellular Movement | 2.28E-15-1.05E-03 | Gastrointestinal Disease | 6.85E-06-6.03E-02 |
| Cellular Development | 4.18E-15-1.09E-03 | Cardiovascular System Development and Function | 8.40E-06-6.03E-02 |
| Neurological Disease | 3.21E-13-1.11E-03 | Molecular Transport | 9.36E-06-6.04E-02 |
| Gene Expression | 3.57E-13-3.95E-04 | Cellular Development | 9.36E-06-5.83E-02 |
| Cardiovascular System Development and Function | 3.57E-13-1.13E-03 | Connective Tissue Development and Function | 9.36E-06-5.48E-02 |
| Organismal Development | 4.85E-13-1.01E-03 | Organismal Development | 9.36E-06-6.03E-02 |
| Gastrointestinal Disease | 1.43E-12-8.91E-04 | Nervous System Development and Function | 1.82E-05-5.83E-02 |
| Infectious Disease | 1.63E-12-6.47E-04 | Tissue Development | 1.82E-05-5.83E-02 |
| Skeletal and Muscular Disorders | 3.74E-12-1.13E-03 | Organ Morphology | 5.23E-05-6.03E-02 |
| Hereditary Disorder | 8.81E-12-8.81E-12 | Lipid Metabolism | 5.97E-05-6.03E-02 |
| Psychological Disorders | 8.81E-12-7.60E-11 | Small Molecule Biochemistry | 5.97E-05-6.03E-02 |