Table 5.

Top 20 functions of predicted gene targets of differentially expressed miRNAs in sera and exosomes

Highly expressed miRNAs in sera		Highly expressed miRNAs in exosomes
Category	B-H p-value	Category	B-H p-value
Cellular Assembly and Organization	6.09E-06-9.75E-02	Cell Death and Survival	6.84E-14-3.44E-02
Cellular Function and Maintenance	6.09E-06-9.75E-02	Cellular Assembly and Organization	8.85E-14-2.77E-02
Molecular Transport	1.09E-05-9.68E-02	Cellular Function and Maintenance	8.85E-14-3.45E-02
Cancer	6.32E-05-9.68E-02	Cellular Growth and Proliferation	4.07E-13-3.45E-02
Cell Death and Survival	9.31E-05-9.68E-02	Cell Morphology	1.09E-10-3.34E-02
Organismal Survival	9.31E-05-6.44E-02	Cellular Movement	8.05E-09-2.79E-02
Cellular Growth and Proliferation	9.31E-05-9.75E-02	Cancer	2.61E-08-3.24E-02
Cell Morphology	2.20E-04-9.75E-02	Molecular Transport	4.45E-07-3.21E-02
Cardiovascular System Development and Function	2.94E-04-9.68E-02	Cardiovascular System Development and Function	8.40E-07-3.43E-02
Organismal Development	2.94E-04-9.68E-02	Organismal Development	8.40E-07-3.45E-02
Infectious Disease	7.70E-04-9.68E-02	Organismal Survival	1.38E-06-2.44E-02
Gene Expression	7.70E-04-9.68E-02	Tissue Development	1.79E-05-3.34E-02
Cellular Movement	8.00E-04-9.68E-02	Gene Expression	2.31E-05-2.13E-02
Cell-mediated Immune Response	1.23E-03-9.68E-02	Cellular Development	2.89E-05-3.45E-02
Cellular Development	1.23E-03-9.75E-02	Nervous System Development and Function	5.47E-05-3.23E-02
Hematological System Development and Function	1.23E-03-9.75E-02	Skeletal and Muscular System Development and Function	6.43E-05-3.23E-02
Hematopoiesis	1.23E-03-9.75E-02	Neurological Disease	6.97E-05-3.18E-02
Lymphoid Tissue Structure and Development	1.23E-03-9.75E-02	Lipid Metabolism	1.19E-04-3.18E-02
Tissue Development	1.82E-03-9.75E-02	Small Molecule Biochemistry	1.19E-04-3.21E-02
Connective Tissue Development and Function	2.01E-03-9.75E-02	Psychological Disorders	1.55E-04-2.44E-02