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. 2016 Aug 12;16:284. doi: 10.1186/s12906-016-1266-y

Table 3.

Minimum inhibitory concentration (MIC) and Minimum bactericidal and fungicidal concentrations (MBC, MFC) of compound 3 from A. ataxacantha

Minimum inhibitory concentrations (μg/ml)
Microorganismsa Gram (+) bacteria Gram (-) bacteria Yeast
S. a S.a.m.r S. ep E. f P. a C. a
3 b 50 25 12.5 25 25 12.5
 Gentamicin 0.39 0.39 0.78 0.39 0.78 Nt
 Fluconazole Nt Nt Nt Nt Nt 0.78
Minimum bactericidal and fungicidal (μg/ml)
3 b 50 50 50 50 25 25
 Gentamicin 0.78 1.56 1.56 0.78 1.56 Nt
 Fluconazole Nt Nt Nt Nt Nt 1.56
MIC index
3 b 1 2 4 2 1 2
 Gentamicin 2 4 2 2 2 Nt
 Fluconazole Nt Nt Nt Nt Nt 2

a S.a : Staphylococcus aureus; S.a.m.r : Staphylococcus aureus methicillin resitant; S.ep : Staphylococcus epidermidis; E.f: Enterococcus faecalis; P.a: Pseudomonas aeruginosa; C.a: Candida albicans

b 3: betulinic acid-3-trans-caffeate

Nt: not tested. MIC, MBC or MFC of compounds 1 and 2 were not determined