Figure 3.

Distributions of T-cell populations within the hematopoietic and lymphoid organs of cynomolgus macaques. (A) Comparison of the percentage of cells in each organ that are CD3⁺. (B) CD3⁺ cells from PB are subdivided into 4 populations (from top left, clockwise: CD4^–CD8⁺, CD4⁺CD8⁺, CD4⁺CD8^–, and CD4^–CD8^–). Between the studied organs, we compared the percentages of (C) CD4⁺CD8^– and (D) CD4^–CD8⁺. CD4⁺ and CD8⁺ single-positive cells can be directly compared by calculating (E) the CD4⁺CD8^–: CD4^–CD8⁺ T cell ratio. We examined the distribution of (F) CD4⁺CD8⁺and (G) CD4^–CD8^– cells in each organ. Data are given as mean ± SEM.