Table 2.
Coronary Computed Tomography Angiography Characteristics of Patients Stratified According to Presence of Any High-risk Plaque
| Total (n = 467) |
High-risk Plaque (n = 167) |
No High-risk Plaque (n = 300) |
p value | |
|---|---|---|---|---|
| Coronary Artery Disease (CAD) category, n (%) | ||||
| No CAD (0% Stenosis) | 207 (44.3) | 0 (0) | 207 (69.0) | — |
| Mild CAD (1–49% Stenosis) | 216 (46.3) | 127 (76.1) | 89 (29.7) | <0.001 |
| Significant CAD (≥ 50% Stenosis) | 44 (9.4) | 40 (24.0) | 4 (1.3) | <0.001 |
| Coronary Artery Calcium Score Category, n (%) | <0.001 | |||
| CACS 0 | 250 (53.5) | 14 (8.4) | 236 (78.7) | |
| CACS 1 – 100 | 137 (29.3) | 93 (55.7) | 44 (14.7) | |
| CACS 101 – 300 | 42 (9.0) | 30 (18.0) | 12 (4.0) | |
| CACS > 300 | 38 (8.1) | 30 (18.0) | 8 (2.7) | |
| Epicardial Fat Measurements, median (iqr) | ||||
| Fat Volume [cc] | 108.5 (76.4 – 140.6) |
123.0 (93.4 – 155.8) |
97.9 (68.2 – 126.5) |
<0.001 |
| Indexed Fat Volume [cc/m2] | 53.7 (37.8 – 69.4) |
59.2 (45.2 – 75.2) |
49.2 (35.2 – 64.9) |
<0.001 |
| Mean Attenuation [HU] | −87.3 (−90.2 – −85.0) |
−88.1 (−90.9 – −85.7) |
−86.9 (−89.9 – −84.7) |
0.008 |
| Paracardial Fat Measurements, median (iqr) | ||||
| Fat Volume [cc] | 79.0 (46.2 – 128.3) |
106.8 (68.9 – 157.1) |
67.8 (42.1 – 103.1) |
<0.001 |
| Indexed Fat Volume [cc/m2] | 40.4 (24.4 – 60.6) |
50.5 (36.1 – 73.3) |
33.4 (22.1 – 52.2) |
<0.001 |
| Mean Attenuation [HU] | −104.8 (−108.9 – −100.5) |
−106.4 (−110.6 – −102.7) |
−103.4 (−107.5 – −99.6) |
<0.001 |
| Total Fat Measurementsa, median (iqr) | ||||
| Fat Volume [cc] | 189.3 (129.1 – 261.2) |
232.8 (169.8 – 324.2) |
166.8 (113.8 – 242.1) |
<0.001 |
| Indexed Fat Volume [cc/m2] | 96.6 (68.1 – 127.0) |
113.4 (86.5 – 149.6) |
84.9 (60.6 – 118.9) |
<0.001 |
| Mean Attenuation [HU] | −94.9 (−98.6 – −91.9) |
−96.9 (−99.7 – −93.8) |
−93.8 (−97.5 – −91.0) |
<0.001 |
CAD = Coronary artery disease; CACS = Coronary artery calcium score;
a
Total fat = epicardial + paracardial fat