Table 1.
Baseline demographics and clinical characteristics.
| Total (N=3094) |
CV event | p -Value | |||
|---|---|---|---|---|---|
| No (N=2587) | Yes (N=507) | ||||
| Gender | Female | 462 (14.9%) | 402 (15.5%) | 60 (11.8%) | 0.032* |
| Male | 2632 (85.1%) | 2185 (84.5%) | 447 (88.2%) | ||
| Race | White | 2855 (92.2%) | 2390 (92.4%) | 465 (91.7%) | |
| Black/African American | 100 (3.2%) | 72 (2.8%) | 28 (5.5%) | ||
| Asian | 40 (1.3%) | 38 (1.5%) | 2 (0.4%) | ||
| Other | 99 (3.2%) | 87 (3.4%) | 12 (2.4%) | ||
| History of myocardial infarction | 1766 (57.1%) | 1469 (56.8%) | 297 (58.6%) | 0.461 | |
| Coronary artery bypass graft | 1136 (36.7%) | 925 (35.8%) | 211 (41.6%) | 0.013* | |
| Percutaneous coronary intervention | 1919 (62.0%) | 1595 (61.7%) | 324 (63.9%) | 0.34 | |
| Stroke or cerebrovascular disease | 655 (21.2%) | 519 (20.1%) | 136 (26.8%) | <0.001* | |
| Peripheral vascular disease | 401 (13.0%) | 320 (12.4%) | 81 (16.0%) | 0.027* | |
| Metabolic syndrome | 2471 (79.9%) | 2061 (79.7%) | 410 (81.0%) | 0.047* | |
| History of diabetes | 1062 (34.3%) | 853 (33.0%) | 209 (41.2%) | <0.001* | |
| History of hypertension | 2212 (71.5%) | 1824 (70.5%) | 388 (76.5%) | 0.006* | |
| Age (years) | Mean ± SD | 63.8 ± 8.72 | 63.7 ± 8.73 | 64.4 ± 8.67 | 0.076 |
| BMI | Mean ± SD | 31.2 ± 5.37 | 31.1 ± 5.31 | 31.6 ± 5.65 | 0.062 |
| HbA1c, % | Mean ± SD | 5.98 ± 0.80 | 5.97 ± 0.78 | 6.07 ± 0.85 | 0.010* |
| eGFR, mL/min/1.73 m2 | Mean ± SD | 77.5 ± 18.5 | 77.8 ± 18.3 | 75.99 ± 19.71 | 0.047* |
| HDL-C, mg/dL (mmol/L) | Mean ± SD | 34.9 ± 5.6 (0.4 ± 0.1) | 35.0 ± 5.7 (0.4 ± 0.1) | 34.3 ± 5.5 (0.4 ± 0.1) | 0.015* |
| HDL3-C, mg/dL (mmol/L) | Mean ± SD | 17.4 ± 2.9 (0.5 ± 0.1) | 17.5 ± 2.9 (0.5 ± 0.1) | 17.1 ± 2.8 (0.4 ± 0.1) | 0.006* |
| HDL2-C, mg/dL (mmol/L) | Mean ± SD | 21.3 ± 3.6 (0.6 ± 0.1) | 21.3 ± 3.7 (0.6 ± 0.1) | 20.9 ± 3.5 (0.5 ± 0.1) | 0.035* |
| LDL-C, mg/dL (mmol/L) | Mean ± SD | 71.1 ± 18.1 (0.8 ± 0.2) | 70.9 ± 18.2 (0.8 ± 0.2) | 71.8 ± 17.5 (0.8 ± 0.2) | 0.293 |
| sdLDL, mg/dL (mmol/L) | Mean ± SD | 32.7 ± 12.8 (0.9 ± 0.3) | 32.6 ± 12.8 (0.9 ± 0.3) | 32.9 ± 12.7 (0.9 ± 0.3) | 0.61 |
| TG, mg/dL (mmol/L) | Mean ± SD | 179.6 ± 65.8 (2.0 ± 0.7) | 179.3 ± 65.5 (2.0 ± 0.7) | 181.0 ± 67.2 (2.1 ± 0.8) | 0.593 |
| LDL-TG, mg/dL (mmol/L) | Mean ± SD | 21.2 ± 6.1 (0.2 ± 0.1) | 21.1 ± 6.1 (0.2 ± 0.1) | 21.4 ± 6.1 (0.2 ± 0.1) | 0.358 |