Figure 4.

A) Confusion matrix and ROC curve generated from a LASSO algorithm which was trained using ‘raw’ neurocognitive tasks scores (see Table 2) to predict individual subjects phenotypic labels. The model predicted individual subjects phenotypic labels with 94% accuracy (sensitivity= 92%, specificity =97%) and area under ROC curve (AUC) = 0.9449. B) Confusion matrix and ROC curve generated from a Elastic Net algorithm which was trained using whole brain fractional anisotropy values to predict individual subjects phenotypic labels. The model predicted individual subjects phenotypic labels with 76% accuracy (sensitivity= 76%, specificity =76%) and area under ROC curve (AUC) = 0.7593.