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. Author manuscript; available in PMC: 2018 Jan 15.
Published in final edited form as: Neuroimage. 2016 Feb 13;145(Pt B):254–264. doi: 10.1016/j.neuroimage.2016.02.016

Table 6.

White matter tracts most relevant in distinguishing individual phenotype I patients from phenotype II patients using the Elastic Net algorithm.

Rank Anatomical region MNI Coordinates (x, y, z) Cluster size *Average beta weight Beta %
1 IFOF -31, 35, 11 92 -5.778 6.56%
2 Mid colossal pathways -22, -30, 43 79 4.379 4.97%
3 Isthmus of the corpus callosum -22, -52, 33 104 3.849 4.37%
4 MFCC 21, 41, 19 108 -2.749 3.12%
5 Cingulum 17, 7, 34 62 0.846 0.96%

IFOF – inferior fronto-occipital fasciculus, MFCC – minor forceps of the corpus callosum.

*

Beta weights were averaged within the cluster. Anatomical regions are listed based on absolute average beta weight within the cluster. Negative beta weights indicate FA reductions in phenotype II patients as compared to phenotype I