Table 3.
FDA approved nerve guidance conduits.
| Product | Material | Structure | Degradation time | Company | FDA-approval |
|---|---|---|---|---|---|
| NeuroTube | Polyglycolic acid | Absorbable woven mesh tube | 3 mo | Synovis Micro Companies | 1999 |
| NeuraGen | Type I collagen | Semipermeable, fibrillar | 3-4 yrs | Integra LifeSciences Co., Plainsboro, NJ, USA | 2001 |
| NeuroFlex | Type I collagen | Semipermeable, flexible, tubular | 4–8 mo | Collagen Matrix, Inc., Franklin | 2001 |
| NeuroMatrix | Type I collagen | Semipermeable, flexible, tubular | 4–8 mo | Collagen Matrix, Inc. | 2001 |
| NeuraWrap | Type I collagen | Semipermeable, longitudinal slit in wall | 36–48 mo | Integra LifeSciences Co. | 2004 |
| NeuroMend | Type I collagen | Semipermeable wrap, unrolls and self-curls | 4–8 mo | Collagen Matrix, Inc. | 2006 |
| Neurolac | Poly-DL-lactide-caprolactone | Synthetic and transparent, tubular | 16 mo | Polyganics BV, Groningen, Netherlands | 2003 |
| SaluTunnel | Polyvinyl alcohol | Nonbiodegradable | No degradation | Salumedica LLC, Atlanta, GA, USA | 2010 |
| Avance | Processed human nerve allograft | AxoGen, Inc., Alachua, FL | 2010 | ||
| AxoGuard | Extracellular matrix derived from porcine small intestine submucosa | Absorbable semipermeable | No data | AxoGen, Inc., Alachua, FL | 2013 |