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. 2016 Jul 31;2016:3856262. doi: 10.1155/2016/3856262

Table 5.

Clinical studies on facial nerve reconstruction with FDA approved nerve guidance conduits.

Study Year Product Type of research Species Defect/pathology Case count Functional recovery attained
Navissano et al. [39] 2005 NeuroTube Case report Human 1–3 cm 7 Yes (71% of the cases)
Dwivedi et al. [40] 2006 NeuraGen Case report Human Hypoglossal-facial anastomosis 1 Yes
Gunn et al. [41] 2010 Avance Case report Human Paraganglioma 1 Yes
Brant et al. [42] 2016 Avance/AxoGuard Technical report Human Facial nerve schwannoma 1 n/a