Table 5.
Clinical studies on facial nerve reconstruction with FDA approved nerve guidance conduits.
| Study | Year | Product | Type of research | Species | Defect/pathology | Case count | Functional recovery attained |
|---|---|---|---|---|---|---|---|
| Navissano et al. [39] | 2005 | NeuroTube | Case report | Human | 1–3 cm | 7 | Yes (71% of the cases) |
| Dwivedi et al. [40] | 2006 | NeuraGen | Case report | Human | Hypoglossal-facial anastomosis | 1 | Yes |
| Gunn et al. [41] | 2010 | Avance | Case report | Human | Paraganglioma | 1 | Yes |
| Brant et al. [42] | 2016 | Avance/AxoGuard | Technical report | Human | Facial nerve schwannoma | 1 | n/a |