(b) Extrapulmonary localization

Signs		Laboratory findings		Signs
Skin, soft tissue	+++	Repeated massive isolation	+++	HIV, systemic organs
Lymphadenitis	++	Repeated isolation	++	Osteoarticular, tenosynovial
	+/−∗	Single isolation	+
AT therapy necessary Lymphadenitis in children, skin: extirpation of affected lymph nodes is of high importance, excision of affected tissue; osteoarticular, tenosynovial, chirurgical debridement; HIV, Haemocultivation.

⁺⁺⁺Strong recommendation for treatment.

⁺⁺Recommendation for treatment.

⁺Weak recommendation for treatment (repeated sample collection necessary), managing intermittent treatment.

⁻No treatment.

^∗Based on isolated MAC species. From invasively taken sample (biopsy, bronchoscopy).

^†Consider contamination, repeated exposition to environmental source, and household screening.