Table 2.
Univariate and multivariate analysis of the variables under study.
| Variable | Not adjusted analysis | Adjusted analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Age | 1.05 (0.97–1.14) | 0.182 | 1.02 (0.91–1.14) | 0.742 |
| Gender | ||||
| Female | 1.0 | |||
| Male | 0.6 (0.26–1.76) | 0.426 | ||
| Child-Pugh | ||||
| Class A | 1.0 | |||
| Class B | 1.65 (0.27–9.86) | 0.584 | 1.55 (0.19–13.7) | 0.665 |
| Class C | 17.9 (3.98–80.8) | 0.01 | 3.42 (0.35–35.8) | 0.288 |
| MELD | 1.33 (1.11–1.60) | 0.02 | 1.22 (0.81–1.6) | 0.251 |
| 6MWT | 0.83 (0.77–0.91) | <0.01 | 0.80 (0.72–0.96) | 0.002 |
| VO 2peak | 0.45 (0.33–0.67) | <0.01 | 0.70 (0.55–0.86) | 0.001 |
| MIP | 0.75 (0.65–0.77) | <0.01 | 0.82 (0.77–0.94) | 0.002 |
| MEP | 0.83 (0.73–0.91) | <0.01 | 1.06 (0.87–1.5) | 0.525 |
MELD: model for end-stage liver disease, 6MWT: six-minute walk test, VO2peak: peak oxygen consumption, MIP: maximum inspiratory pressure, and MEP: Maximum Expiratory Pressure. HR = hazard ratio; analysis adjusted by age, Child-Pugh score, MELD, 6MWT, VO2peak, MIP, and MEP (p < 0.2).