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. 2016 Jul 31;2016:2656814. doi: 10.1155/2016/2656814

(b).

Advanced stage at diagnosis IPTW

Unadjusted odds ratios and 95% confidence intervals
OR 95% CI Sig.

Metformin
 Yes 0.69 [0.49, 0.95]
 No Ref.

Adjusted odds ratios and 95% confidence intervals
AOR 95% CI Sig.

Metformin
 Yes 0.68 [0.48, 0.97]
 No Ref.

Notes: based on the data of 2,652 elderly men aged 66 years and older diagnosed with prostate cancer between 2008 and 2009 using a surveillance, epidemiology, and end-results- (SEER-) Medicare linked data. % is weighted percentage for IPTW. Significant differences are based on the log-likelihood test using a logistic regression with IPTW weights. Adjusted model controlled for predisposing, enabling, need, and external environment related factors.

IPTW: inverse probabilities treatment weights; PSA: prostate specific antigen level; PCP: primary care physician visit; Sig.: level of significance; ∗∗∗ p < 0.001; ∗∗0.001 ≤ p < 0.01; 0.01 ≤ p < 0.05.