Table 2.
Time point | Men | Women | |||||
---|---|---|---|---|---|---|---|
Unadjusted | BMD change | 95 % CI | *P | BMD change | 95 % CI | *P | **P |
Baseline | 0.8116 | (0.7849, 0.8384) | REF | 0.7144 | (0.6911, 0.7378) | REF | *0.84 |
Δ T2 | −0.0061 | (−0.0257, 0.0136) | 0.54 | −0.0027 | (−0.0228, 0.0175) | 0.79 | 0.81 |
Δ T6 | −0.0018 | (−0.0293, 0.0257) | 0.89 | −0.0025 | (−0.0273, 0.0223) | 0.84 | 0.97 |
Δ T12 | −0.0189 | (−0.0463, 0.0083) | 0.17 | −0.0022 | (−0.0297, 0.0252) | 0.87 | 0.39 |
Unadjusted | % Change | 95 % CI | *P | % Change | 95 % CI | *P | **P |
Baseline | REF | REF | REF | REF | REF | REF | *0.84 |
Δ T2 | −0.75 | (−3.18, 1.68) | 0.54 | −0.38 | (−3.20, 2.45) | 0.79 | 0.81 |
Δ T6 | −0.22 | (−3.62, 3.17) | 0.89 | −0.35 | (−3.82, 3.12) | 0.84 | 0.97 |
Δ T12 | −2.35 | (−5.72, 1.03) | 0.17 | −0.32 | (−4.16, 3.53) | 0.87 | 0.39 |
Adjusted | BMD change | 95 % CI | *P | BMD change | 95 % CI | *P | **P |
Baseline | 0.7856 | (0.7574, 0.8139) | REF | 0.7461 | (0.7171, 0.7751) | REF | *0.90 |
Δ T2 | −0.0078 | (−0.0250, 0.0093) | 0.37 | −0.003 | (−0.0188, 0.0128) | 0.70 | 0.67 |
Δ T6 | −0.0157 | (−0.0371, 0.0056) | 0.14 | −0.0103 | (−0.0276, 0.0070) | 0.24 | 0.68 |
Δ T12 | −0.0191 | (−0.0441, 0.0058) | 0.13 | −0.0066 | (0.0281, 0.0149) | 0.54 | 0.45 |
Adjusted | % Change | 95 % CI | *P | % Change | 95 % CI | *P | **P |
Baseline | REF | REF | REF | REF | REF | REF | *0.90 |
Δ T2 | −0.99 | (−3.18, 1.18) | 0.37 | −0.41 | (−2.53, 1.72) | 0.7 | 0.67 |
Δ T6 | −2.01 | (−4.73, 0.72) | 0.14 | −1.38 | (−3.71, 0.94) | 0.24 | 0.68 |
Δ T12 | −2.44 | (−5.61, 0.74) | 0.13 | −0.88 | (−3.77, 2.01) | 0.54 | 0.45 |
P values for the sex- and time-specific changes;
P values for the *global test of the sex by time interaction and time-specific sex differences. Adjusted for potential confounders: race, age, weight, height, smoking, alcohol use, bisphosphonates, glucocorticoids, hormone therapy, calcium supplements, comorbidity count, instrumental activities of daily living, center for epidemiologic studies depression scale, and DXA measurement site
BMD bone mineral density, CI confidence interval