Skip to main content
. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Cell Immunol. 2016 May 27;306-307:17–24. doi: 10.1016/j.cellimm.2016.05.004

Figure 4. iNOS inhibition abrogates EPO-mediated suppression.

Figure 4

Figure 4

Figure 4

Panel A: EPO-mediated suppression is blocked by 1-MA. C57BL/6J PerC cells were cultured with (left to right) anti-CD3, anti-CD3 + 1-MA, anti- CD3 + 100 ng/ml EPO, anti-CD3 + 100 ng/ml EPO + 1-MA. Panel B: EPO effect is absent in IFNγR−/− PerC cells. Left to right, C57BL/6J PerC cells with anti-CD3, anti-CD3 + 100 ng/ml EPO; IFNγR−/−cells with anti- CD3, anti-CD3 + 100 ng/ml EPO. Panel C: EPO effect is absent in iNOS−/− PerC cells. Left to right, C57BL/6J PerC cells with anti-CD3, anti-CD3 + 100 ng/ml EPO; iNOS−/−cells with anti-CD3, anti-CD3 + 100 ng/ml EPO.