Table 3. Treatment and Outcomes.

Pt	Treatment	Renal Function	Re-treated with CPI?	IRAEs with re-treatment?	AKI with re-treatment?
1	Pred 60mg daily, tapered off over 3 months	Partial recovery	Pembro	No	No
2	Pred 60mg daily, tapered off over 6 weeks	Complete recovery	No	NA	NA
3	Episode 1: Pred 60mg daily, tapered off over 2 weeks; Episode 2: hydrocortisone 100mg IV q12 hours × 1 day, then prednisone 60mg daily, tapered to 10 mg daily over 3 months and continued at 10mg daily for an additional 3 months	Partial recovery	No	NA	NA
4	Conservative management	No recovery	No	NA	NA
5	Solumedrol 35mg IV daily × 4 days, then Pred 80mg daily, tapered off over 8 weeks	Partial recovery	No	NA	NA
6	Solumedrol 500mg IV daily × 3 days, 250mg IV daily × 3 days, then pred 80mg daily, tapered off over 4 weeks	No recovery	No	NA	NA
7	Pred 70mg BID, tapered over 3 weeks to 10mg daily, tapered off over 9 weeks	Partial recovery	Ipi	Colitis	No
8	Pred 60mg daily, tapered off over 2 weeks	No recovery	No	NA	NA
9	Solumedrol 500mg IV daily × 3 days, then Pred 60mg daily; 2 weeks later Pred increased to 80mg BID and MMF 1g BID added	Partial recovery	No	NA	NA
10	Conservative management	No recovery	Ipi	No	No
11	Pred 60mg daily × 4 weeks, then tapered off over 8 weeks	Partial recovery	No	NA	NA
12	Solumedrol 500mg IV daily × 3 days, then Pred 40mg daily, tapered off over 4 weeks	Partial recovery	No	NA	NA
13	Solumedrol 250mg × 1, then Pred 40 mg daily, tapered off over 3 months	Complete recovery	No	NA	NA

Abbreviations: CPI, checkpoint inhibitor; IRAEs, immune-related adverse events; MMF, mycophenolate mofetil; NA, not applicable; Pembro, pembrolizumab; Pred, prednisone.