. Author manuscript; available in PMC: 2017 Oct 1.

Published in final edited form as: Neurobiol Dis. 2016 Jun 17;94:85–94. doi: 10.1016/j.nbd.2016.06.008

Table 1.

Effects of chronic HIV-1 protein expression in vivo on the membrane properties in rat mPFC pyramidal neurons.

	SAL-non-Tg	SAL-HIV-1 Tg	Dilt/Mem-non-Tg	Dilt/Mem-HIV-1 Tg
RMP (mV)	−68.8 ± 0.9	−67.0 ± 1.0	−68.8 ± 1.7	−68.3 ± 1.3

R_in (MΩ)	184.4 ± 10.1	221.1 ± 10.6^*	169.9 ± 19.9	203.1 ± 15.1
Rheobase (pA)	88.8 ± 6.0	70.0 ± 6.5^*	102.8 ± 10.8	88.5 ± 9.0

Threshold (mV)	−40.2 ± 0.6	−39.9 ± 0.6	−39.9 ± 1.1	−39.6 ± 0.9

1/2 amplitude duration (ms)	1.08 ± 0.05	1.16 ± 0.05	1.20 ± 0.09	1.31 ± 0.07

Amplitude (mV)	71.1 ± 1.8	60.9 ± 1.8^***	77.4 ± 3.3	67.6 ± 2.6^*^{^}

AHP (mV)	−16.1 ± 0.6	−15.6 ± 0.6	−16.0 ± 1.0	−14.6 ± 0.8

Two-way ANOVA. HIV-1 Tg vs. non-Tg:

:p≤0.05,

^***

:p≤0.001;

SAL-HIV-1 Tg vs. Dilt/Mem-HIV-1 Tg:

^{^}

:p≤0.05.

A significant effect of treatment regardless of genotype was observed for 1/2 amplitude duration (dark gray box).