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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Drug Alcohol Depend. 2016 Jun 25;166:249–253. doi: 10.1016/j.drugalcdep.2016.06.021

Table 1.

SKAT_CommonRare results.

DSM-5 CUD DSM-5 MSU
Gene # Tested markers (%rarea) Qb P-value Q P-value
CNR1 5 (0%) 306.68 0.2736 34.571 0.3241
FAAH 6 (66.67%) 5.728 0.0035c 2.499 0.1066
MGLL 6 (83.33%) 0.989 0.6195 1.051 0.5675
DAGLA 4 (75%) 2.535 0.0898 2.666 0.0814
DAGLB 9 (77.78%) 1.236 0.6352 1.167 0.6526
a

The MAF cutoff for common vs rare variants is calculated in SKAT as follows: 1/ √[2 SampleSize]

b

The test statistic of SKAT

c

Survived Bonferroni correction for multiple testing at p < 0.004