Table 2.
Characteristics of intracerebral hemorrhage (ICH) versus ischemic stroke (IS) in CF-LVAD patients
| ICH (n=8) | IS (n=32) | p-value | |
|---|---|---|---|
| Pre LVAD history | |||
| Age (years) | 52.3 ± 13.3 | 55.3 ± 14.5 | 0.591 |
| Women | 2 (25.0%) | 5 (15.6%) | 0.611 |
| Body surface area (m2) | 2.1 ± 0.4 | 2.0 ± 0.3 | 0.452 |
| Ischemic | 3 (37.5%) | 17 (53.1%) | 0.695 |
| Hypertension | 6 (75.0%) | 16 (50.0%) | 0.258 |
| Hyperlipidemia | 2 (25.0%) | 14 (43.8%) | 0.439 |
| Diabetes | 4 (50.0%) | 17 (53.1%) | 0.999 |
| Smoking history | 3 (37.5%) | 11 (34.4%) | 0.999 |
| Creatinine (mg/dl) | 1.59 ± 0.65 | 1.46 ± 0.71 | 0.629 |
| Previous stroke | 1 (12.5%) | 2 (6.3%) | 0.498 |
| Previous TIA/stroke | 1 (12.5%) | 2 (6.3%) | 0.498 |
| Device Type | |||
| HeartMate II | 4 (50.0%) | 26 (81.3%) | 0.089 |
| HVAD | 4 (50.0%) | 6 (18.8%) | |
| Device Strategy | |||
| BTT | 4 (50.0%) | 20 (62.5%) | 0.690 |
| DT | 4 (50.0%) | 12 (37.5%) | |
| Post LVAD history | |||
| GI Bleeding | 2 (25.0%) | 9 (28.1%) | 0.999 |
| Device-related infection | 2 (25.0%) | 6 (18.8%) | 0.650 |
| Sepsis | 3 (37.5%) | 9 (28.1%) | 0.677 |
| Pump exchange for thrombosis | 1 (12.5%) | 5 (15.6%) | 0.999 |
| At the time of stroke | |||
| Duration of support | 284.9 ± 346.1 | 233.8 ± 312.2 | 0.688 |
| INR (for patients on warfarin) | 3.03 ± 1.28 (4 pts) | 2.23 ± 0.6 (24 pts) | 0.301 |
| PTT (for patients on heparin) | 81.1 ± 14.1 (4 pts) | 67.9 ± 20.5 (5 pts) | 0.309 |
| NIHSS | 10.3 ± 12.8 | 9.6 ± 9.4 | 0.170 |
| Outcome post stroke | |||
| Survival to discharge home or rehab | 3 (37.5%) | 23 (71.9%) | 0.102 |
Values are n (%).
ICH = Intracerebral hemorrhage; IS = Ischemic Stroke; CF-LVAD = Continuous-Flow Left Ventricular Assist Device; TIA = Transient Ischemic Attack; HVAD = Heartware Left Ventricular Assist Device; BTT = Bridge to Transplant; DT = Destination Therapy; GI = Gastrointestinal; INR = International Normalized Ratio; PTT = Partial Thromboplastin Time; NIHSS = National Institutes of Health Stroke Scale.