Table 2.
Material components | Temperature (°C) | T1 relaxation time ± SD (ms) | T2 relaxation time ± SD (ms) | Apparent Diffusion Coefficient ± SD (10−6 mm2/s) | |
---|---|---|---|---|---|
Fibroglandular tissue mimic | 35% Corn syrup w/w in water | 17.91 | 1096.65 ± 6.35 | 236.33 ± 6.97 | 966 ± 5 |
19.07 | 1115.53 ± 9.95 | 236.43 ± 2.13 | 1013 ± 21 | ||
20.16 | 1151.58 ± 9.81 | 241.38 ± 8.99 | 1030 ± 7 | ||
22.11 | 1200.15 ± 8.57 | 262.18 ± 6.77 | 1084 ± 10 | ||
Adipose tissue T1 and spectral shift mimic | Grapeseed oil: Chemical shift from water 3.10 ppm | 17.91 | 227.45 ± 2.13 | 41.30 ± 1.11 | |
19.07 | 230.48 ± 2.31 | 42.30 ± 1.95 | |||
20.16 | 238.63 ± 4.01 | 42.40 ± 1.59 | |||
22.11 | 249.28 ± 4.64 | 43.93 ± 1.67 | |||
Diffusion mimics: Benign lesion | 10% PVP w/w in water | 17.91 | 2015.25 ± 24.80 | 1536 ± 7 | |
19.07 | 2026.73 ± 24.66 | 1627 ± 25 | |||
20.16 | 2127.95 ± 39.20 | 1630 ± 12 | |||
22.11 | 2172.60 ± 65.13 | 1714 ± 6 | |||
Malignant lesion | 14% PVP | 17.91 | 1720.70 ± 18.12 | 1348 ± 4 | |
19.07 | 1732.00 ± 12.98 | 1407 ± 7 | |||
20.16 | 1817.83 ± 10.82 | 1439 ± 11 | |||
22.11 | 1903.15 ± 22.23 | 1522 ± 6 | |||
Malignant mass | 18% PVP | 17.91 | 1490.53 ± 20.42 | 1238 ± 9 | |
19.07 | 1518.93 ± 28.02 | 1307 ± 15 | |||
20.16 | 1628.23 ± 13.26 | 1318 ± 8 | |||
22.11 | 1704.85 ± 24.43 | 1389 ± 7 | |||
25% PVP | 17.91 | 1050.55 ± 6.80 | 861 ± 12 | ||
19.07 | 1073.35 ± 9.20 | 907 ± 15 | |||
20.16 | 1125.88 ± 15.28 | 927 ± 9 | |||
22.11 | 1182.48 ± 8.05 | 983 ± 12 | |||
40% PVP | 17.91 | 630.30 ± 1.61 | 557 ± 9 | ||
19.07 | 651.97 ± 6.88 | 600 ± 17 | |||
20.16 | 681.53 ± 3.33 | 602 ± 10 | |||
22.11 | 723.97 ± 16.68 | 640 ± 9 |
All measurements were made on a 1.5 T small bore MRI system using spin-echo sequences, specifically: inversion recovery method to measure T1, variable echo for T2, and three gradient directions with b-values of 0, 100, 600 and 900 s/mm2 for ADC measurements. Determination of standard deviation is described in the Methods.