Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 15;7:149. doi: 10.3389/fgene.2016.00149

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Carey, Agrawal, Bucholz, Hartz, Lynskey, Nelson, Bierut and Bogdan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Cross-disorder polygenic risk scores and general substance involvement liability. Y-axis is the percent of variation in GENSUB explained by CROSS PRS. Shades of gray in legend indicate the p-value threshold (i.e., p < 0.0001, 0.001, 0.01, 0.05, 0.1, 0.2, 0.3, 0.4, 0.5, or 1.0) at which the risk score was calculated based on the results of the original cross-disorder meta-analysis. CROSS, cross-psychiatric-disorder. GENSUB, general substance involvement liability. PRS, polygenic risk score.