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. 2016 Aug 15;7:253. doi: 10.3389/fphar.2016.00253

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Copyright © 2016 Tong, Wang, Wang, Liu, Sun, Li, Su and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of sodium propionate on macrophages with CD68 marker in the colonic tissue. Macrophages were determined by immunofluorescence in colonic tissues. CD68 was used as the marker of macrophage/monocyte infiltration in the colon of mice and visualized by fluorescence microcopy (green staining). Nuclei were stained with DAPI (blue staining). Arrows indicate CD68-labeled macrophages in the colon. Images were representative of 6–8 mice in each group. Scar bars were 100 μm. Morphometric analysis of macrophages in the colon was also performed. Data are presented as mean ± SD. n = 6–8 per group, ^∗P < 0.05, ^∗∗P < 0.01 vs. control group; ^#P < 0.05, ^##P < 0.01 vs. DSS group.