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. 2016 Aug 15;7:1265. doi: 10.3389/fmicb.2016.01265

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Copyright © 2016 Campisi, Rosini, Ji, Guidotti, Rojas-López, Geng, Deng, Zhong, Wang, Liu, Nan, Margarit and Rinaudo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of antibiotic resistance genes and phenotypes in the 14 GBS isolates selected for whole genome sequencing (WGS). Heatmap representing the copy number of antibiotic resistance genes present in each genome. The antimicrobial susceptibility was assessed by E test determining the minimal inhibitory concentrations (MICs) to streptomycin (Sm), spectinomycin (Sc), kanamycin (Km), azithromycin (Az), claritromycin (Ch), erythromycin (Em), clindamycin (Cm), tetracycline (Tc), lincomycin (Lm), levofloxacin (Le), gentamycin (Gm), benzylpenicillin (Pg), ceftriaxone (Tx), vancomycin (Va). R, antibiotic resistant. All strains were susceptible to penicillin, ceftriaxone, vancomycin, levofloxacin, and gentamycin. COH1 was used as reference genome in the in silico resistome analysis and as reference strain in the antimicrobial susceptibility tests.