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. 2016 Aug 15;7:1265. doi: 10.3389/fmicb.2016.01265

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Copyright © 2016 Campisi, Rosini, Ji, Guidotti, Rojas-López, Geng, Deng, Zhong, Wang, Liu, Nan, Margarit and Rinaudo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sequence comparison of the newly identified ICESag (RR2) and ICE SGB76 from S. agalactiae. An example of composite ICESag (RR2) found in GBS GZ02, GZ20, GZ06, GZ11, and CS01 isolates. Coding sequences (CDSs) are depicted by arrows. Dotted lines represent the region of insertion of a new genetic module resembling the GBS ICE SGB76 carrying antibiotic resistance genes (red arrows). Green shadowing indicates 99% of sequence identity. Brown arrows indicate genes duplicated in ICESag (RR2).