Table 2.
Putative gene identifications for SNP loci
| Locus No. | Gene name | Gene function | SNP location and effect |
|---|---|---|---|
| 1 | Atrial Natriuretic Peptide | Hormone activity; regulation of blood pressure | 3′ UTR |
| 2 | Chymotrypsinogen | Hydrolase activity; digestion |
Coding (CGT to CGC) Arg To Arg (Synonymous) |
| 3 | Ribosomal protein S2 | Protein synthesis |
ACT to ACC Thr to Thr (Synonymous) |
| 4 | Translationally controlled tumor protein | Transcription factor binding; negative regulator of apoptosis | 3′ UTR |
| 5 | Ribosomal protein | Protein synthesis |
Coding (GAG to GGG) Glu to Gly (Nonconservative) |
| 6 | Guanine nucleotide binding protein (G‐protein), beta polypeptide 2 like 1; also called RACK1 | Receptor of activated protein kinase C1 (RACK1); apoptosis |
Coding (ACC to ACT) Thr to Thr (Synonymous) |
| 7 | NACA; nascent polypeptide‐associated complex subunit alphalike protein | DNA binding; cardiac development |
Coding (GTA to GAA) Val to Glu (Nonconservative) |
| 8 | Titin cap | Sarcomere assembly; muscle |
Coding (GAG to GAC) Glu to Asp (Nonconservative) |
| 9 | SNP name 1176_169; Probable intergenic region; No annotated gene (nearest neighbor gene gamma‐aminobutyric acid (GABA) receptor type B subunit 2) | Unknown | Intergenic |
| 10 | 60S ribosomal protein L6 (RPL6) | Protein synthesis; translation |
Coding (GGG to GGC) Gly to Gly (Synonymous) |
| 11 | Parvalbumin | Calcium binding; muscle |
Coding (GCT to GCC) Ala to Ala (Synonymous) |
| 12 | Actin‐binding LIM protein family 3; SNP located in intron | Cytoskeleton organization; muscle | Intron |
| 13 | Myoglobin | Oxygen binding | 3′ UTR |
| 14 | 60S ribosomal protein L35 | Protein synthesis; translation |
Coding (GGC to GGT) Gly to Gly (Synonymous) |
| 15 | 40S ribosomal protein S17 | Protein synthesis; translation |
Coding (AGT to AGC) Ser to Ser (Synonymous) |
| 16 | Cytochrome oxidase I (COXI) | Electron transport chain; Mitochondrially encoded |
Coding (GGC to GGT) Gly to Gly (Synonymous) |
| 17 | Cytochrome B | Electron transport chain; Mitochondrially encoded |
Coding (CTC to CTT) Leu to Leu (Synonymous) |
| 18 | SLC25A | Phosphate carrier; mitochondrial localization |
Coding (GCG to GCC) Ala to Ala (Synonymous) |
| 19 | HD domain containing 2 (HDDC2); SNP located in intron | Function Unknown; probable mitochondrial localization | Intron |
| 20 | Warm acclimation‐related protein (Wap65); Hemopexin | Heme binding; oxidative stress |
Coding (GCG to GTG) Ala to Val (Nonconservative) |
| 21 | Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) | Glycolysis | 3′ UTR |
| 22 | Tropomyosin | Muscle contraction |
Coding (GAA to GAG) Glu to Glu (Synonymous) |
| 23 | Lactate dehydrogenase_B (SNP 654) | Glycolysis |
Coding (TCC to GCC) Ser to Ala (Nonconservative) |
| 24 | Chymotrypsin‐C | Pancreatic peptidase |
Coding (GAA to GAG) Glu to Glu (Synonymous) |
| 25 | Nucleoside diphosphate kinase 1 | Biosynthesis; nucleotide synthesis |
Coding (GAG to GAC) Glu to Asp (Conservative) |
| 26 | Lactate dehydrogenase‐B (SNP 1033) | Glycolysis |
Coding (GCC to GAC) Ala to Asp (Nonconservative) |
| 27 | Hemoglobin alpha | Oxygen transport |
Coding (CCA to GCA) Pro to Ala (Nonconservative) |
| 28 | Cytochrome p450 (Cyp3A4) | Metabolism; Monooxygenase |
Coding (ATC to GTC) Ile to Val (Conservative) |
| 29 | 14‐3‐3 zeta | Signaling | 3′ UTR |
| 30 | Hemoglobin beta | Oxygen transport |
Coding (AGT to AGC) Ser to Ser (Synonymous) |
| 31 | Nucleoside diphosphate kinase 2 | Biosynthesis; nucleotide synthesis | 3′ UTR |
| 32 | Intergenic 1173 | Unknown | Noncoding |