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. 2016 Jul;14(5):427–434. doi: 10.2174/1570159X13666150425002304

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© 2016 Bentham Science Publishers

This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

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Fig. (2) — Recovery of the cingulate LTD in tail amputation model mice by priming. (A) High concentration of DHPG (100 μM) together with MPEP (10 μM) were applied for 20 min in the tail amputation model mice. After washout for 50 min, low-frequency stimulation (1 Hz for 15 min) shows cingulate LTD. (B) DHPG (20 μM) together with MPEP (10 μM) were applied for 15 min in sham group. After washout for 15 min, the low-frequency stimulation produces LTD. (C) In tail amputation model mice, DHPG with MPEP were given for 15 min. After washout for 15 min, the stimulation induces cingulate LTD. Modified from [29].