Table 1.

Summary of differences in effect of each transferred mutation across recipient strains

Mutation	Range	F	df*	P
rbs	0.94–1.07	3.436	11,76	<0.001
topA	0.96–1.25	21.95	5,75	<0.001
spot	0.84–1.09	11.29	10,103	<0.001
pykF	0.97–1.29	23.98	22,323	<0.001

^*Degrees of freedom differ between mutations because they were introduced into overlapping but not identical sets of strains (Fig. 1 and see SI Materials and Methods for details).