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Quaternary structure of Rep, Ant, and the Rep–Ant complex and the solution structure of the Rep92–198 tetramer. (A) Rep (red line), Ant (black line), and the Rep–Ant complex (blue line) were analyzed by SEC-MALS. The dotted line represents the measured molecular mass. (B) Overall crystal structure of the Rep92–198 tetramer and magnified stereo view showing details of the interaction at the interface of two Rep92–198 dimers. Each chain is shown in a different color.
