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Difference Fourier electron density maps of GDPCP and the catalytic switch I loop in EF-4. (A) Minimally biased Fobs – Fcalc difference Fourier map of GDPCP (cyan) in EF-4 bound to the ribosome. Residues forming the catalytic switch I loop are shown in yellow. (B) Same as in A, but showing the Fobs – Fcalc map of the catalytic switch I loop in EF-4. The maps are contoured at ∼2.5σ.
