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Annals of Oncology logoLink to Annals of Oncology
. 2016 Jun 21;27(Suppl 2):ii78. doi: 10.1093/annonc/mdw199.259

P-269: Results of combined surgical treatment locally advanced cancer of the rectum with germination in genital organs

A Abdujapparov 1, S Djanklich 1
PMCID: PMC4984054

Introduction: Given the fact that in 55-60% of cases, colorectal cancer is diagnosed in stages 3-4 of the disease, there is a trend to increase the number of patients with spread to the organs of the genitals in women.

Methods: We have analyzed the combined results of operations for cancer of the rectum with germination in genital organs, performed in Department of Coloproctology National Сancer Research Center for 2008 - 2014. Under our observation were 118 women aged from 21 to 68 years. The nature of operations on the rectum with combined surgical procedures was as follows: abdominoperineal extirpation of the rectum with resection sigmoid colon was performed in 57 patients (48,3%), abdominal-anal resection of the rectum in 22 patients (18,6%), anterior resection of the rectum in 12 patients (10.2%) Hartmann's operation was performed in 27 patients.

Results: The most commonly combined surgical procedures were performed resection of the vagina - 58 patients, supravaginal amputation of uterus without appendages 21, extirpation of uterus with appendages - in 22 patients, removal of the uterus - in 31 patients. It should be noted that 14 patients of these patients were resection or deleted more than one organ. It is important to note that metastatic involvement of regional lymph nodes are installed at 28,0% of patients (33 of 118), whereas for all radical surgery the figure was 29.1%. Postoperative complications suppurative-inflammatory character appeared in 21 cases (17,7%). Total mortality was 3,4%, have died after combined surgery 4 patients from 118 operated patients. The frequency of occurrence of relapse after combined surgery for cancer of the rectum was 28%. The average duration without recurrent period was 14 months. The 5-year survival after combined surgery in locally spread rectal cancer in our study was 47.1%.

Conclusion: Thus, these data indicate that important indicators such as the frequency of recurrence (28%), 5-year survival rate (47,1%), under combined interference and operations standard volume for carcinoma of the rectum about the same. Given that the true tumor invasion into surrounding structures is often possible to establish only after histological research of the removed macropreparation and that combined surgical intervention at the present time practically does not worsen the immediate results of treatment.


Articles from Annals of Oncology are provided here courtesy of Oxford University Press

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