Table 2.
Setting of LDCT annual screening entry criteria and comparisons | 1. Total CT Examinations, Including Screening, setting NLST at 100% as reference | 2. Screening Detected Cases, setting NLST at 100% as reference | 3. Reduction in Lung Cancer mortality in % | 4. Total Cases Detected at an Early Stage, % | 5. Average Screening Examinations per Person Screened, N | 6. Screening Examinations per Lung Cancer Death Averted, N | 7. Screening Examinations per Life-Year Gained, N | 8. Average False-Positive Results per Person Screened, N | 9. Over-diagnosis % of all cases | 10. Over-diagnosis % of screening-detected cases | 11.Radiation-Related Lung Cancer Deaths, N |
---|---|---|---|---|---|---|---|---|---|---|---|
NLST | 100 | 100 | 12.3 | 48.4 | 13.8 | 577 | 49 | 3.2 | 2.7 | 8.7 | 24 |
USPSTF vs. NLST | + 8.2 | +19.7 | +1.7 | +2.1 | +1.1 | +3 | +3 | +0.4 | +1.0 | +1.2 | +0 |
Our study* vs. NLST | +29.0 | +39.0 | +3.5 | +3.7 | +3.1 | +6 | +5 | +0.7 | +1.6 | +1.3 | +1 |
Our study* vs. USPSTF | +19.3 | +16.1 | +1.8 | +1.6 | +2.0 | +3 | +2 | +0.5 | +0.6 | +0.1 | +1 |
Derived and adapted from Tables 1-2 of de Koning et al, Annals of Internal Medicine, 2014.
Used a screening program most similar to A-55-80-30-25 in de Koning et al, Annals of Internal Medicine, 2014 (i.e., A-55-80-30-30):