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. 2016 Jan 21;5(3):227–235. doi: 10.1002/open.201500216

Scheme 2.

Scheme 2

General synthetic method to 4,4′‐dimethoxytrityl compounds 520 E–H. Reagents and conditions: a) 4,4′‐dimethoxytrityl chloride, (2.8 equiv), pyridine (4.5 mL mmol−1), 80 °C, 18 h; b) 4,4′‐dimethoxytrityl chloride, (2.8 equiv), DMAP (2.8 equiv), pyridine (4.5 mL mmol−1), 80 °C, 18 h.