Table 2. Blood analyses.
Blood was collected via retro-orbital bleeds from anesthetized mice and analyzed using an iStat instrument and EC8+ cartridges. Data are the mean +/− SEM; n=11 for each group. P values are calculated by two tailed unpaired Student’s t test.
| WT | F233Δ | p | |
|---|---|---|---|
| Na, mEq/L | 145.0 3.0 | 145.5 ± 1.3 | 0.695 |
| K, mEq/L | 4.3 ± 0.8 | 4.5 ± 0.5 | 0.309 |
| Cl, mEq/L | 113.9 ± 1.9 | 110.5 ± 1.5 | 0.003 |
| HCO3, mEq/L | 22.8 ± 1.9 | 26.5 ± 1.9 | 0.001 |
| BUN, mg/dL | 23.1 ± 3.9 | 19.0 ± 1.3 | 0.116 |
| Glu, mg/dL | 206.5 ± 24.8 | 204.9 ± 36.5 | 0.911 |
| Hct, % | 42.5 ± 2.3 | 43.3 ± 1.7 | 0.496 |
| pH | 7.2 ± 0.1 | 7.2 ± 0.1 | 0.426 |
| pCO2, mmHg | 59.4 ± 9.6 | 65.1 ± 6.0 | 0.096 |
| AG | 12.5 ± 2.5 | 13.0 ± 2.2 | 0.630 |
| Hgb, g/dL | 14.5 ± 0.8 | 14.7 ± 0.6 | 0.534 |