Table 1. Mean composite score of CCR6-positive cells in colon cancer tissues.
|
Percentage of CCR6-positive cells |
|||||
|---|---|---|---|---|---|
|
Adenocarcinoma |
|||||
| CCR6 immuno-intensity level | N | N0 | N1 | N2 | M1 |
| +1 | 12.52 (1) | 1.86 (1) | 0.97 (1) | 1.87 (1) | 1.27 (1) |
| +2 | 24.05 (1) | 12.68 (1) | 10.29 (1) | 13.32 (1) | 8.22 (1) |
| +3 | 49.9 (2) | 69.17 (3) | 71.32 (3) | 71.70 (3) | 64.25 (3) |
| +4 | 13.53 (1) | 16.29 (1) | 17.42 (1) | 13.11 (1) | 26.26 (2) |
| Mean composite score | 13 | 16 | 16 | 16 | 20 |
| P-value compared with normal adjacent | — | <0.01 | <0.001 | <0.01 | <0.001 |
Immunostaining was scored based on the immuno-intensity of CCR6, where +1=weak, +2=moderate, +3=high and +4=very high intensity. Number in parentheses represents the scoring level for percentage of CCR6-positive cells in the respective immuno-intensity category. Mean composite score was calculated by summation of intensity score multiplied by percentage score of CCR6-positive cells.