Table 3. Relationship between levels of Δsv-MALAT1 and FL-MALAT1 and a panel of RTK/MAPK/PI3K proteins in a panel of 143 breast tumours.

	Δsv-MALAT1		FL-MALAT1
	ra	P-valuea	ra	P-valuea
RTK proteins (n=9)
EGFR	0.068	NS	0.033	NS
p.EGFR.Thr669	0.008	NS	−0.047	NS
p.EGFR.Tyr1173	0.036	NS	0.052	NS
Her2/ErbB2	0.091	NS	−0.032	NS
Her3/ErbB3	−0.128	NS	0.000	NS
p.Her3/Erbb3.Tyr1289	−0.060	NS	−0.020	NS
p.Her4.Tyr1162	0.108	NS	0.018	NS
Met	−0.025	NS	−0.029	NS
p.Met.Tyr1234.1235	−0.064	NS	−0.026	NS
MAPK pathway proteins (n=4)
MEK1/2	−0.029	NS	−0.073	NS
p.MEK1/2.Ser217/221	0.113	NS	−0.047	NS
p44.42.MAPK	0.116	NS	0.150	NS
p.p44.42.MAPK.Thr202.Tyr204	0.127	NS	0.030	NS
PI3K/AKT pathway proteins (n=15)
PTEN	0.101	NS	0.050	NS
p.PTEN.Ser380.Thr382.383	−0.018	NS	−0.026	NS
INPP4b	0.001	NS	0.042	NS
Akt1	0.030	NS	−0.017	NS
p.Akt1.Ser473	0.119	NS	−0.032	NS
Akt2	−0.102	NS	0.028	NS
mTor	−0.155	NS	−0.066	NS
p.mTor.Ser2448	−0.077	NS	0.008	NS
FOXO1	−0.194	0.0210	−0.196	0.0180
TSC2	−0.075	NS	0.003	NS
p70.S6.Kinase	−0.172	0.0400	0.099	NS
p.p70.S6.Kinase.Thr389	−0.225	0.0070	0.073	NS
S6.Ribosomal.protein	−0.034	NS	0.075	NS
p.S6.Ribosomal.protein.Ser235.236	−0.095	NS	0.006	NS
p.S6.Ribosomal.protein.Ser240.244	−0.201	0.0160	−0.024	NS

Abbreviations: Akt=protein kinase B, also known as Akt; EGFR=epidermal growth factor receptor; MAPK=mitogen-activated protein kinase; mTor=mechanistic target of rapamycin; NS=not significant; PI3K=phosphoinositide 3-kinase; PTEN=phosphatase and tensin homologue.

^aSpearman's rank correlation test.