TABLE II.
Organomegaly and bone marrow findings
| Patient counts |
|||||
|---|---|---|---|---|---|
| Tryptase level* | Severe mediator symptoms, yes or no | Organomegaly, yes or no | No bone marrow biopsy performed | Bone marrow biopsy performed | No. with + bone narrow result†/no. with bone marrow biopsy performed |
| <20 | Yes | Yes | 0 | 1 | 1/1 |
| ≥20 | Yes | Yes | 0 | 16 | 16/16 |
| Not done | Yes | Yes | 0 | 1 | 1/1 |
| <20 | No | Yes | 0 | 0 | 0 |
| ≥20 | No | Yes | 0 | 1 | 1/1 |
| Not done | No | Yes | 0 | 0 | 0 |
| <20 | Yes | No | 2 | 8 | 0/8 |
| ≥20 | Yes | No | 6 | 9 | 0/9 |
| Not done | Yes | No | 0 | 17 | 0/17 |
| <20 | No | No | 31 | 0 | 0 |
| ≥20 | No | No | 5 | 0 | 0 |
| Not done | No | No | 8 | 0 | 0 |
| Totals | 52 | 53 | 19/53 | ||
*
Measurement in proximity to the time a decision about performing a bone marrow was made.
†
Bone marrow biopsy revealed systemic disease. The bone marrow procedure was performed at an age range of 1 to 18 years, with a mean of 4.76 years. The time of performance of the bone marrow biopsy after age of onset was a mean of 4.57 years.