Computed three dimensional structure of NDM-5 (created with UCSF
Chimera 1.10). a Ribbon structure of
NDM-5 coloured in rainbow style. Metal ions coloured grey. b
Surface topology of NDM-5 coloured by Coulombic surface colouring. Surface
calculated using AMBER ff 14SB charge model on three colour scale of
red, −10 kcal/(mol e), white,
0 kcal/(mol e), and blue, 10 kcal/(mol e), where e is unit
electron charge. c Predicted binding
clefts of NDM-5