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Cytotoxicity testing of selected compounds against target cell lines or pooled, stimulated human PBMCs from healthy donorsa
| Target cells | CC50 (μM) |
||
|---|---|---|---|
| GRP-71271 | GRP-103594 | GRP-115249 | |
| MDCK | >100 | >100 | >100 |
| BEAS-2B | >100 | >100 | >100 |
| Vero | >100 | >100 | >100 |
| BSR T7/5 | >100 | >100 | >100 |
| Hep2 | >100 | >100 | >100 |
| Stimulated human PBMCs | >100 | >100 | ND |
The highest concentration assessed was 100 μM. ND, not determined.
