FIG 5.

Decreased thiol content and inhibited expression of IL-12 p40 mRNA in macrophages infected with LP-BM5. The levels of GSH, cysteine, LP-BM5d DNA, and IL-12 p40 in murine peritoneal macrophages infected with 0.5 and 1 unit of RT were analyzed at 3 and 6 days postinfection. Infection of the macrophages and evaluation of the different parameters were performed as described in Materials and Methods. Values represent the means ± SDs for 3 samples. *, P < 0.05 versus uninfected mice at the same time point; **, P < 0.01 versus uninfected mice at the same time point; ***, P < 0.005 versus uninfected mice at the same time point. nr, number.