TABLE 1.
Demographic and clinical characteristics of study subjects and numbers of sequencing readsa
| Characteristic | Value for group |
|
|---|---|---|
| Early-stage subjects (n = 6) | Late-stage subjects (n = 30) | |
| Median age (yr) (IQR) | 40.5 (27.5–49) | |
| No. (%) of male patients | 6 (100) | |
| Median most recent CD4 cell count (cells/μl) (IQR) | 600 (556–617) | 23 (13–41) |
| Median most recent HIV RNA level (log10 copies/ml) (IQR) | 4.64 (4.30–4.83) | 5.2 (5.0–5.4) |
| Median no. of days after infection (IQR) | 328 (135–448) | NA |
| Median no. of TCSs (IQR) | 1,532 (1,332–1,883) | 1,357 (992–1,982) |
| Median sequencing depth (%) (IQR)b | 0.2 (0.16–0.22) | 0.22 (0.15–0.33) |
a
IQR, interquartile range; TCS, template consensus sequence; NA, not applicable.
b
Sequencing depth is defined as the lowest abundance of a variant that can be detected with a 95% chance of a certain number of TCSs.