FIG 7.

Vaccine efficacy of DB1 in cotton rats. Groups of 6 cotton rats were infected i.n. with DB1 or RSVA/Tracy or served as uninfected controls. Animals were challenged with RSVA/Tracy on day 42 p.i., and viral loads were measured 4 days later by standard plaque assays of lung lavage (A) and nasal wash (B) fluids. Each symbol represents a single animal. Data represent means ± SDs. Dotted lines indicate the limits of detection (LOD). ***, P < 0.0005; ****, P < 0.00005 by one-way ANOVA and Tukey multiple-comparison test.