FIG 3.

There are no differences in apoptosis or in proliferation in spleen-derived T cells. Splenocytes from naive WT and Mavs^−/− mice were harvested, labeled with 2.5 μM CFSE, and cultured in the presence of 1 μg anti-CD3 MAb. After 66 h, cells were harvested and stained for caspase 8 (A), caspase 3/7 (B), BCL-2 (C), and CFSE dilution (D). (A and B) Left panels indicate WT mice; right panels indicate Mavs^−/− mice.