FIG 2.

Spread patterns in the presence and absence of DIPs. Representative time lapse images of three major spread patterns on BHK-21 cells infected with reporter VSV at an MOI of 30 and their DIPs at various multiplicities are shown. Bars, 200 μm. Normal plaques (top) emerged from cells infected at all MODIP levels, but primarily at a MODIP of 0 or a low MODIP (0.1 or 1). Slow-growing (center) and patchy (bottom) plaques were observed only in the presence of DIPs (MODIP levels, 1 and 10). Time points are shown above the panels. Since the patchy plaques developed more slowly than the others, an additional image at 35 hpi is shown. See also Movies S1 to S3 in the supplemental material.