TABLE 3.
Effects of model parameters on simulated infection spread
| Parameter | Effecta on: |
|||
|---|---|---|---|---|
| Adsorption efficiency (kad) | Clearance rate (kc) | Superinfection period (tsup) | Diffusion constant (D) | |
| Spread rate | ↓ | ↓ | ↓ | ↑ for D of >0.1 |
| Delay in spread | ↔ | ↔ | ↔ | ↓ |
| Relative fluorescence around P.C. | ↑ | ↑ | ↓ | ↓ for D of <0.1, ↑ for D of >0.1 |
| Infected fraction around P.C. | ↓ | ↓ | ↑ | ↑ |
| Fraction of fully inhibited spread | ↑ | ↑ | ↔ | ↓ for D of <0.1 |
↑, increasing with an increase in the parameter (P < 0.01); ↓, decreasing with an increase in the parameter (P < 0.01); ↔, no significant change (P > 0.01).