Structural comparison of the region composed of residues 562 and 564 of AAV1, -2, -4, and -5. The atomic alignments of AAV2 residues 562 and 564, which are universally conserved in all serotypes by amino acid alignment, were compared and found to have atomic structures that were virtually identical to those of both the closely related serotypes AAV1 (purple) and AAV2 (blue) and the distantly related serotypes AAV4 (red) and AAV5 (gray).