FIG 7.

Postnatal antibody development in rhesus macaques. The analysis of plasma and salivary antibodies was performed using cross-sectional samples from infant macaques (black symbols) between the ages of 0 (birth) to 7 months (Mo). Adult antibody levels (open diamonds) are shown for comparison. The number of animals in each group is listed in parentheses below the relevant age group. Plasma and salivary total IgG levels (A and B) and plasma and salivary IgA levels (C and D) in infant compared to adult macaques are shown. Each symbol represents an individual animal, with horizontal bars indicating the median value. The nonparametric Mann-Whitney test was performed to determine differences between two specific infant age groups and between 6- to 7-month-old infants and adults. Note that a monomeric serum IgA standard was used to measure the polymeric IgA. Therefore, the total IgA is likely to be underestimated by a factor of 2.5.