Table 1. Absolute and percentage changes (mean±s.d.) in perfusion and R 2* for SW1222 metastases treated with OXi4503 (n=6), LS174T metastases treated with OXi4503 (n=3) and SW1222 metastases given saline control (n=5).
| SW1222+OXi4503 | LS174T+OXi4503 | SW1222+Saline | |
|---|---|---|---|
|
Perfusion | |||
| Tumours (ml g−1 min−1) | −0.49±0.44 | 0.04±0.23 | −0.17±0.31 |
| % | −43±33*** | 61±152 | −16±39* |
| Liver (ml g−1 min−1) | −0.35±0.28 | −0.14±0.45 | −0.54±0.28 |
| % | −12±12 | −10±27 | −26±15 |
|
R2* | |||
| Tumours (s−1) | 5±28 | 13±12 | 11±16 |
| % | 0±26 | 28±25*** | 6±10 |
| Liver (s−1) | 12±10 | 16±10 | 8±12 |
| % | 9±11 | 13±11 | 5±7 |
The internal control of the liver has been included for each group. Stars denote the significance determined by Wilcoxon tests (*P<0.05, **P<0.01, ***P<0.001).