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. 2016 May;24(2):62–73. doi: 10.1179/2042618613Y.0000000047

Table 5.

Characteristics of included studies

Study Population Intervention Comparison Reported outcomes
Andersen et al.16 RCT 198 participants (174 women, 24 men) HEP only: shoulder abduction (lateral raise), exercise to target perceived, ‘relevant neck and shoulder muscles’ 5 times per week During weeks 1–2, participants used moderate resistance training with elastic tubing. During weeks 2–4, participants progressed to higher level of resistance Control group=weekly educational emails containing information including general health and physical activity. Internet links regarding this information were also provided Clinically relevant reductions in pain and tenderness as well as muscle strength increases were found in approximately half of the participants of the training groups As little as 2 minutes of daily progressive resistance training for 10 weeks results in clinically relevant reductions of pain and tenderness and increased muscles strength in adults with frequent neck/shoulder symptoms
Mean age: 12-minute group:
2-minute group: 44 (±11) Weeks 1–2=5–6 sets of 8–12 repetitions
12 minute group: 42 (±11) control group: 43 (±10) Weeks 2–4=6 sets of 12 repetitions 2-minute group:
Chronic neck pain with/or without shoulder pain for the previous 3 months lasting at least 30 days within 1 year28,29 Weeks 1–2=single set until failure or until 2 minutes
Weeks 2–4=increased resistance band
Bronfort et al.17 RCT 272 patients; aged 18–65 years old Within clinic treatment of spinal thrust/ non-thrust decided by the provider group lasting 15–20 minutes Home exercise with advice (HEA): instructional 1-hour sessions (×2) SMT had statistically significant advantage over medication at 26 weeks. No important differences in pain were found between SMT and HEA at any time point
Mean age:
SMT group: 48.3 (±15.2) placed 1–2 weeks apart for home exercise of ‘self-mobilization’ of gentle controlled general movements of neck retraction, extension, flexion, rotation, lateral bending motions, and scapular retraction (with no resistance)
Med group: 46.8 (±12.2) 5–10 repetitions of each exercise up to 6–8 times per day
HEA group: 48.6 (±12.5) Medication group:
Sub-acute non-specific neck pain for 2–12 weeks28,29 visits lasted 15–20 minutes. Non-steroidal anti-inflammatory drugs, acetaminophen, or both. Participants who did not respond to or could not tolerate drugs received narcotic medications or muscle relaxants
Hall et al.18 RCT 32 subjects, mean±SD age, 36±3 years Chronic cervicogenic headache (CHA) for past 3 months28,29 HEP only: The control group was involved in a sham self-mobilization at C1–C2 using the cervical self-SNAG strap C1–C2 self-SNAG reduced cervicogenic headache symptoms on the headache severity index over 1 year compared to the control group
The experimental group: C1–C2 self-SNAG. Position held for 3 seconds, 2 repetitions of the exercise, twice daily for 12 months The strap was positioned in the same way at the experimental group, but the subject did not turn their head when they applied the 3-second sustained forward pressure at C1
Kuijper et al.19 RCT 205 patients, ages 18–75 years Cervical collar group: Control group: patients were advised to continue daily activities and document their normal routine Treatment with a cervical collar plus rest or PT plus home exercises resulted in a statistically significant reduction of arm and neck pain compared to the control group
Mean age:
collar group: 47 (±9.1)
semi-hard collar throughout the day for 3 weeks With the control group, disability index score improved by 9 points on the neck disability
PT: 46.7 (±10.9) Weeks 3–6=patients were weaned from the collar until week 6 where they were advised to terminate the use of the collar Physiotherapy with HEP Both the cervical collar and the PT groups disability index score improved by 14 points
control: 47.7 (±10.6) Physiotherapy group:
Acute/sub-acute cervical radiculopathy, <1 month in duration28,29 clinical treatment of deep and
superficial neck muscle exercises twice
a week for 6 weeks in duration
HEP: isometric and chin retraction exercises, 2 sets of 10 repetitions
Mongini et al.20 RCT 1040 participants between 43 and 52 HEP only Control group: one-month diary for daily recording of the presences, severity of their headache and neck/shoulder pain, and their intake of analgesics (by type) Intervention group showed a higher respondent rate for headache and for neck/shoulder pain, and a larger reduction in the days per month with headache
Mean age: Intervention group:
intervention group: 48
control group: 47
relaxation exercises: concentrated craniofacial-cervical facial relaxation for 1 repetition 2 times daily
Chronic headache, neck/shoulder pain28,29 posture retraining of upright standing, horizontal forward and backward head movements, and isometric extension (counter-pressure): 8–10 repetitions, every 2–3 hours
Nikander et al.11 RCT 180 female office workers aged 25–53 years All three groups were encouraged to perform aerobic exercise 3 times/week for 30 minutes The control group received written information with the same stretching exercises as the training groups to complete three times/week for 20 minutes One MET-hour of training per week accounted for an 0.8-mm decrease of neck pain on the Visual Analog Scale (VAS) and a 0.5-mm decrease on the Disability Index; a training dose of 20 MET(hour) per month represented a 16-mm decline in the VAS
Mean Age:
strength group: 45 (±6) Both training groups exercised 3 times/ week and also completed a single series of squats, sit-ups, and back extensor
endurance group: 45 (±6) exercises as well as 20 minutes of stretching
control group: 46 (±5) HEP only:
Constant or frequent chronic neck pain and disability occurring.6 months28,29 Both groups attended a 12-day rehabilitation period to learn exercises followed by performing exercises for 12 months at home The effective dose of the specific training program to decrease chronic neck pain was 8.75 MET(hour) per week on a scale of 1.5 (light work) to 10 (extremely heavy work)
Strength training group
targeted neck muscles with rubber band 1 set of 15 repetitions 3 times/week at a resistance level of 80% patient’s maximum isometric strength from baseline
upper body exercises 1 set of 15 repetitions (4–13 kg gradually increasing the load) with dumbbell including dumbbell shrugs, presses, curls, bent-over rows, flies, and pullovers Endurance-training group:
trained neck muscles in supine position by lifting up head in 3 sets of 20 repetitions 3 times/week
same upper body exercises as the strength training group with 2 kg dumbbells with 3 sets of 20 repetitions
Salo et al.21 RCT 180 female office workers, ages 25–53 years HEP only: The control group received written information with the same stretching exercises as the training groups to complete three times/week for 20 minutes Both training groups had statistically significant score improvements as shown with the HRQoL 15D measurement tool. There was no change in the control group (P=0.012). The strength training group improved in 5 of 15 dimensions and the endurance-training group improved in 2 dimensions. 12-month follow-up: both the strength or endurance training seemed to moderately enhance the HRQoL of female patients with chronic neck pain
Mean age: Both groups attended a 12-day rehabilitation period to learn exercises followed by performing exercises for 12 months at home
strength group: 45 (±6) Strength training group:
endurance group: 45 (±6) trained neck muscles with rubber band 1 set of 15 repetitions 3 times/week at a resistance
control group: 46 (±5) level of 80% patient’s maximum isometric strength from baseline
Constant or frequent chronic neck pain and disability occurring >6 months28,29 upper body exercises 1 set of 15 repetitions (4–13 kg gradually increasing the load) with dumbbell including dumbbell shrugs, presses, curls, bent-over rows, flies, and pullovers
Endurance-training group:
trained neck muscles in supine position by lifting up head in 3 sets of 20 repetitions 3 times/week
same upper body exercises as the strength training group with 2 kg dumbbells with 3 sets of 20 repetitions